DNA vaccines are one of the type of third generation vaccines that are based on the purified plasmid preparation that contains transgenes which is capable of encoding antigenic proteins that triggers an immune response against the infectious diseases. DNA Vaccine technology has numerous advantages over other traditional vaccination and therapeutics techniques in terms of ease of fabrication, efficacy, safety and stability. As of year 2016, human related applications of DNA vaccines are under clinical trials, however animal DNA vaccines are available in commercial market. Global DNA vaccine market is anticipated to rise with a CAGR of about 55% during the forecast years 2016-2023. Increase in the clinical trials of DNA based vaccine for the treatment of infectious diseases can be observed in the market. For example, National Institute of Allergy and Infectious Diseases (NIAID), a part of national institute of health is leading a clinical trials for DNA based vaccine and aims to include total of 2,490 healthy participants in those areas where a confirmed or potential active mosquito-transmitted Zika infection has been recorded. These areas includes the United States, Brazil, Puerto Rico, Costa Rica, Peru, Panama and Mexico. Surging investments in the development of third generation vaccination technology is driving global DNA vaccines market. Some other factors that includes rising prevalence of chronic and infectious diseases, increasing adoption of DNA vaccines for animal healthcare and low cost of DNA vaccines as compared to other gene therapy technologies also helps to increase the market growth.
Fast growth projected in the DNA vaccination market once they get approval in clinical trials has attracted majority of investors to deviate their investments for strong returns. About 100 clinical trials are in the progress for humans for the wide range of diseases that includes Cancer, HIV, Hepatitis, zika infection, influenza and other infectious diseases. The Melinda gates foundation has provided a fund of about $100 million to the Moderna therapeutics for the development of DNA vaccines for the infectious disease. Furthermore, government departments are also funding the development of DNA vaccines to the private companies. For instance, US department of health and services agreed to provide a fund of about $125 million to the Moderna therapeutics for the development of vaccine for Zika infection. Similarly, HIV vaccine and trial network provided a funding of $23.5 million to the Inovio for the development of Pennvax-B. These investments has propelled the growth in research and development activities of the DNA vaccine market.
The report on global DNA vaccine market includes DNA Vaccine type, technology and application.
DNA vaccine type are segmented into:
- Animal DNA vaccines
- Human DNA vaccines
DNA vaccine technologies are segmented into:
- Plasmid DNA vaccines technology
- Plasmid DNA delivery technology
The applications of DNA vaccines market include:
- Human disease applications
o Oncology
o Infectious diseases
o Allergies
o Others
- Veterinary disease applications
o Canine melanoma
o Leishmaniasis
o Equine West Nile Virus
o Others
The report scope is widely categorized on the basis of sales of animal DNA vaccines along with current investments in research and clinical trials of human DNA vaccines. As there is no product for human DNA vaccine in the market for sale as of year 2016, the report excludes any real-time revenue figure from sales and its forecast in human segment by type. The report widely covers DNA vaccine technologies and delivery technologies. Viral vector vaccines have also been excluded from the scope of study.
The global DNA vaccine market report has been geographically segmented into:
- North America (U.S. & Canada)
- Asia Pacific (China, India, Japan and RoAPAC)
- Europe (UK, France, Germany, Spain and RoE)
- Rest of World
North America region dominates the market among other regions. Increasing prevalence of infectious and chronic diseases in countries such as the US and Canada is driving the demand of effective vaccination technology. Mortality rate due to chronic and infectious disease has increased in United States to about 360,000 every year. Furthermore, interest of governments agencies such as National institute of health, National institute of allergy and infectious disease and others in the development of DNA based vaccines has also helped to promote the market growth in the United States. Asia pacific market is anticipated to be the fastest growing region due to rising awareness among consumers regarding the advantages of immunization in case of Hepatitis B and H1N1 influenza. In countries such as China, state food and drug administration designated 11 biotech companies for the H1N1 vaccines. These companies include Sinovac, Haiwang interlong, SIBS, Hualan Bio and others.
Among the segment of DNA vaccine type, Animal DNA vaccine is a leading the market due to unavailability of human DNA vaccines in the market along with rising incidence of canine melanoma and other animal diseases. Canine melanoma accounts to about 7% of all canine skin tumours cases globally. Moreover, after the entry of human DNA vaccines, this segment is expected to grow at a fast pace. Among the application segment, the veterinary applications are leading the market due to availability of DNA vaccines for animal diseases that includes canine melanoma vaccine (DOG), West Nile Innovator (Horse), Life tide-SW5 (Swine and other food animals) and Apex-IHN (Salmon fish).
The major market players of the global DNA vaccine market are:
- Novartis Animal Health
- Inovio Biomedical Corp.
- Merck & Co.
- Vical Inc.
- Others
These companies using various strategies such as merger & acquisition, collaboration, partnership and product launch. Whereas, merger & acquisition is the key strategy adopted by the companies in the global DNA vaccine market.
For example, On 10th August 2015, the global biological research and development arm of AstraZeneca, Medimmune entered into a licence agreement and cancer vaccine collaboration with Inovio Pharmaceuticals. The agreement covers clinical stage cancer vaccine INO-3112 HPV and collaboration for preclinical development of additional cancer vaccine candidates. Under the agreement, Medimmune has been granted with an exclusive rights for INO-3112 immunotherapy of Inovio pharmaceutical that targets the cancer causing human papilomavirus of type 16 and 18. The INO-3112 is under the clinical trials for head, neck and cervical cancers. This vaccine works by generating a response of killer T cell that destroys tumours driven by Human papilomavirus type16 and 18.
Key reason to buy the report:
- The report includes market estimation, forecast and analysis for the year 2016-2023
- Report includes detailed analysis of different segments such as DNA vaccines type, technology and applications in DNA vaccine market.
- Identify and understand the strength, opportunities, challenges and threat of the DNA Vaccines market.
- Covers details analysis of Porters 5 force model and other strategic models and also covers revenues, market share analysis, and competitive landscape analysis of major players of DNA vaccine market.
- Detailed analysis of various the regulatory policies which are affecting the global DNA vaccine market.
How we are different from others:
At Occam’s we provide an extensive portfolio which is comprehensive market analysis along with the market size, market share, and market segmentations. Our report on global DNA vaccine market offers detailed analysis of strategic models such as investment vs. adoption model, see saw analysis and others strategic models. Also, the report contains the detailed analysis of application, adoption scenario and decision support for each segment. The report discusses competitive landscape of the DNA vaccine market, with giving extensive SCOT analysis of key companies.
Key findings of the global DNA Vaccine market.
- Surging investments in the development of third generation vaccination technology is driving strong growth in the global DNA vaccine market.
- North America held highest revenue share in 2016.
- Animal DNA Vaccine segment holds the largest market among DNA Vaccination type segments due to increase in animal oriented cancer diseases globally.
- Collaboration and agreements are the key strategy adopted by the market players of DNA vaccine market.